The SSBP3 co-regulator is required for glucose homeostasis, pancreatic islet architecture, and beta-cell identity

OBJECTIVE: Transcriptional complex activity drives the development and function of pancreatic islet cells to allow for proper glucose regulation. Prior studies from our lab and others highlighted that the LIM-homeodomain transcription factor (TF), Islet-1 (Isl1), and its interacting co-regulator, Ld...

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Detalles Bibliográficos
Autores principales: Toren, Eliana, Kepple, Jessica D., Coutinho, Kristen V., Poole, Samuel O., Deeba, Iztiba M., Pierre, Tanya H., Liu, Yanping, Bethea, Maigen M., Hunter, Chad S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448474/
https://www.ncbi.nlm.nih.gov/pubmed/37536498
http://dx.doi.org/10.1016/j.molmet.2023.101785

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