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Adaptive evolution of a minimal organism with a synthetic genome

The bacterial strain JCVI-syn3.0 stands as the first example of a living organism with a minimized synthetic genome, derived from the Mycoplasma mycoides genome and chemically synthesized in vitro. Here, we report the experimental evolution of a syn3.0- derived strain. Ten independent replicates wer...

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Detalles Bibliográficos
Autores principales: Sandberg, Troy E., Wise, Kim S., Dalldorf, Christopher, Szubin, Richard, Feist, Adam M., Glass, John I., Palsson, Bernhard O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448532/
https://www.ncbi.nlm.nih.gov/pubmed/37636038
http://dx.doi.org/10.1016/j.isci.2023.107500