Contribution of local regeneration of glucocorticoids to tissue steroid pools

11β-Hydroxysteroid dehydrogenase 1 (11βHSD1) is a drug target to attenuate adverse effects of chronic glucocorticoid excess. It catalyses intracellular regeneration of active glucocorticoids in tissues including brain, liver and adipose tissue (coupled to hexose-6-phosphate dehydrogenase, H6PDH). 11...

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Detalles Bibliográficos
Autores principales: Khan, S, Livingstone, D E W, Zielinska, A, Doig, C L, Cobice, D F, Esteves, C L, Man, J T Y, Homer, N Z M, Seckl, J R, MacKay, C L, Webster, S P, Lavery, G G, Chapman, K E, Walker, B R, Andrew, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448579/
https://www.ncbi.nlm.nih.gov/pubmed/37343234
http://dx.doi.org/10.1530/JOE-23-0034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448579/
https://www.ncbi.nlm.nih.gov/pubmed/37343234
http://dx.doi.org/10.1530/JOE-23-0034

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