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Is N-methylacetazolamide a possible new therapy against ischemia-reperfusion injury?

The increase of intracellular Ca(2+) concentration, produced principally by its influx through the L-type Ca(2+) channels, is one of the major contributors to the ischemia-reperfusion injury. The inhibition of those channels in different experimental models was effective to ameliorate the post-ische...

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Detalles Bibliográficos
Autores principales: Pardo, Alejandro Ciocci, Díaz Zegarra, Leandro A., González Arbeláez, Luisa F., Aiello, Ernesto A., Mosca, Susana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448815/
https://www.ncbi.nlm.nih.gov/pubmed/37637427
http://dx.doi.org/10.3389/fphar.2023.1223132