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Prediction of G4 formation in live cells with epigenetic data: a deep learning approach
G-quadruplexes (G4s) are secondary structures abundant in DNA that may play regulatory roles in cells. Despite the ubiquity of the putative G-quadruplex-forming sequences (PQS) in the human genome, only a small fraction forms G4 structures in cells. Folded G4, histone methylation and chromatin acces...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448861/ https://www.ncbi.nlm.nih.gov/pubmed/37636021 http://dx.doi.org/10.1093/nargab/lqad071 |