In Vitro 3D Spheroid Culture System Displays Sustained T Cell-dependent CLL Proliferation and Survival

Chronic lymphocytic leukemia (CLL) cells are highly dependent on microenvironmental cells and signals. The lymph node (LN) is the critical site of in vivo CLL proliferation and development of resistance to both chemotherapy and targeted agents. We present a new model that incorporates key aspects of...

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Detalles Bibliográficos
Autores principales: Haselager, Marco V., van Driel, Bianca F., Perelaer, Eduard, de Rooij, Dennis, Lashgari, Danial, Loos, Remco, Kater, Arnon P., Moerland, Perry D., Eldering, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448932/
https://www.ncbi.nlm.nih.gov/pubmed/37637994
http://dx.doi.org/10.1097/HS9.0000000000000938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448932/
https://www.ncbi.nlm.nih.gov/pubmed/37637994
http://dx.doi.org/10.1097/HS9.0000000000000938

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