Targeted chain-exchange-mediated reconstitution of a split type-I cytokine for conditional immunotherapy

Antibody-cytokine fusions targeted against tumor-associated antigens (TAAs) are promising cancer immunotherapy agents, with many such molecules currently undergoing clinical trials. However, due to the limited number of tumor-specific targets, on-target off-tumor effects can lead to systemic toxicit...

Descripción completa

Detalles Bibliográficos
Autores principales: Vasic, Vedran, Buldun, Can, Ritz, Manfred, Dickopf, Steffen, Georges, Guy J., Spick, Christian, Peuker, Alessa, Meier, Thomas, Mayer, Klaus, Brinkmann, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448976/
https://www.ncbi.nlm.nih.gov/pubmed/37608616
http://dx.doi.org/10.1080/19420862.2023.2245111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448976/
https://www.ncbi.nlm.nih.gov/pubmed/37608616
http://dx.doi.org/10.1080/19420862.2023.2245111

Ejemplares similares