Significant expansion of the donor pool achieved by utilizing islets of variable quality in the production of allogeneic “Neo-Islets”, 3-D organoids of Mesenchymal Stromal and islet cells, a novel immune-isolating biotherapy for Type I Diabetes

Novel biotherapies for Type 1 Diabetes that provide a significantly expanded donor pool and that deliver all islet hormones without requiring anti-rejection drugs are urgently needed. Scoring systems have improved islet allotransplantation outcomes, but their use may potentially result in the waste...

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Detalles Bibliográficos
Autores principales: Gooch, Anna M., Chowdhury, Sabiha S., Zhang, Ping M., Hu, Zhuma M., Westenfelder, Christof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449143/
https://www.ncbi.nlm.nih.gov/pubmed/37616230
http://dx.doi.org/10.1371/journal.pone.0290460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449143/
https://www.ncbi.nlm.nih.gov/pubmed/37616230
http://dx.doi.org/10.1371/journal.pone.0290460

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