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What is a minimal clinically important difference for clinical trials in patients with disorders of consciousness? a novel probabilistic approach

Over the last 30 years, there has been a growing trend in clinical trials towards assessing novel interventions not only against the benchmark of statistical significance, but also with respect to whether they lead to clinically meaningful changes for patients. In the context of Disorders of Conscio...

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Detalles Bibliográficos
Autores principales: Monti, Martin M., Spivak, Norman M., Edlow, Brian L., Bodien, Yelena G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449161/
https://www.ncbi.nlm.nih.gov/pubmed/37616196
http://dx.doi.org/10.1371/journal.pone.0290290