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The phenuivirus Toscana virus makes an atypical use of vacuolar acidity to enter host cells

Toscana virus is a major cause of arboviral disease in humans in the Mediterranean basin during summer. However, early virus-host cell interactions and entry mechanisms remain poorly characterized. Investigating iPSC-derived human neurons and cell lines, we found that virus binding to the cell surfa...

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Detalles Bibliográficos
Autores principales: Koch, Jana, Xin, Qilin, Obr, Martin, Schäfer, Alicia, Rolfs, Nina, Anagho, Holda A., Kudulyte, Aiste, Woltereck, Lea, Kummer, Susann, Campos, Joaquin, Uckeley, Zina M., Bell-Sakyi, Lesley, Kräusslich, Hans-Georg, Schur, Florian KM., Acuna, Claudio, Lozach, Pierre-Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449198/
https://www.ncbi.nlm.nih.gov/pubmed/37578957
http://dx.doi.org/10.1371/journal.ppat.1011562