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Kynurenic acid, a key L-tryptophan-derived metabolite, protects the heart from an ischemic damage

BACKGROUND: Renal injury induces major changes in plasma and cardiac metabolites. Using a small- animal in vivo model, we sought to identify a key metabolite whose levels are significantly modified following an acute kidney injury (AKI) and to analyze whether this agent could offer cardiac protectio...

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Detalles Bibliográficos
Autores principales: Bigelman, Einat, Pasmanik-Chor, Metsada, Dassa, Bareket, Itkin, Maxim, Malitsky, Sergey, Dorot, Orly, Pichinuk, Edward, Kleinberg, Yuval, Keren, Gad, Entin-Meer, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449225/
https://www.ncbi.nlm.nih.gov/pubmed/37616231
http://dx.doi.org/10.1371/journal.pone.0275550