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Direct endothelial ENaC activation mitigates vasculopathy induced by SARS-CoV2 spike protein

INTRODUCTION: Although both COVID-19 and non-COVID-19 ARDS can be accompanied by significantly increased levels of circulating cytokines, the former significantly differs from the latter by its higher vasculopathy, characterized by increased oxidative stress and coagulopathy in lung capillaries. Thi...

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Detalles Bibliográficos
Autores principales: Romero, Maritza J., Yue, Qian, Singla, Bhupesh, Hamacher, Jürg, Sridhar, Supriya, Moseley, Auriel S., Song, Chang, Mraheil, Mobarak A., Fischer, Bernhard, Zeitlinger, Markus, Chakraborty, Trinad, Fulton, David, Gan, Lin, Annex, Brian H., Csanyi, Gabor, Eaton, Douglas C., Lucas, Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449264/
https://www.ncbi.nlm.nih.gov/pubmed/37638055
http://dx.doi.org/10.3389/fimmu.2023.1241448