TIMP2 facilitates CIRI through activating NLRP3-mediated pyroptosis

This study aimed to investigate the underlying mechanisms of cerebral ischemia-reperfusion injury (CIRI) in mice using CIR and hypoxia/reoxygenation (H/R) cell models. The study evaluated brain tissue weight, pathological injury, and changes in the expression levels of TIMP2, p-ERK1/2 and NLRP3-medi...

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Detalles Bibliográficos
Autores principales: Shi, Shaoyong, Zhang, Chongyang, Liu, Jiaxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449283/
https://www.ncbi.nlm.nih.gov/pubmed/37178321
http://dx.doi.org/10.18632/aging.204696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449283/
https://www.ncbi.nlm.nih.gov/pubmed/37178321
http://dx.doi.org/10.18632/aging.204696

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