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Ling Zhi-8, a fungal immunomodulatory protein in Ganoderma lucidum, alleviates CPT-11-induced intestinal injury via restoring claudin-1 expression

CPT-11 (Irinotecan) remains an important chemotherapeutic agent against various solid tumors nowadays. Potential adverse effects, especially gastrointestinal toxicities, are the main limiting factor for its clinical utility. Ling Zhi-8 (LZ-8), a fungal immunomodulatory protein in Ganoderma lucidum m...

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Detalles Bibliográficos
Autores principales: Li, Ju-Pi, Chu, Ching-Liang, Chao, Wan-Ru, Yeh, Cheng-Siang, Lee, Yi-Ju, Chen, Dz-Chi, Yang, Shun-Fa, Chao, Yu-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449289/
https://www.ncbi.nlm.nih.gov/pubmed/37155145
http://dx.doi.org/10.18632/aging.204695