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In vitro and in vivo effects of zoledronic acid on senescence and senescence-associated secretory phenotype markers

In addition to reducing fracture risk, zoledronic acid has been found in some studies to decrease mortality in humans and extend lifespan and healthspan in animals. Because senescent cells accumulate with aging and contribute to multiple co-morbidities, the non-skeletal actions of zoledronic acid co...

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Detalles Bibliográficos
Autores principales: Samakkarnthai, Parinya, Saul, Dominik, Zhang, Lei, Aversa, Zaira, Doolittle, Madison L., Sfeir, Jad G., Kaur, Japneet, Atkinson, Elizabeth J., Edwards, James R., Russell, Graham G., Pignolo, Robert J., Kirkland, James L., Tchkonia, Tamar, Niedernhofer, Laura J., Monroe, David G., Lebrasseur, Nathan K., Farr, Joshua N., Robbins, Paul D., Khosla, Sundeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449299/
https://www.ncbi.nlm.nih.gov/pubmed/37154858
http://dx.doi.org/10.18632/aging.204701