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In vitro and in vivo effects of zoledronic acid on senescence and senescence-associated secretory phenotype markers
In addition to reducing fracture risk, zoledronic acid has been found in some studies to decrease mortality in humans and extend lifespan and healthspan in animals. Because senescent cells accumulate with aging and contribute to multiple co-morbidities, the non-skeletal actions of zoledronic acid co...
Autores principales: | Samakkarnthai, Parinya, Saul, Dominik, Zhang, Lei, Aversa, Zaira, Doolittle, Madison L., Sfeir, Jad G., Kaur, Japneet, Atkinson, Elizabeth J., Edwards, James R., Russell, Graham G., Pignolo, Robert J., Kirkland, James L., Tchkonia, Tamar, Niedernhofer, Laura J., Monroe, David G., Lebrasseur, Nathan K., Farr, Joshua N., Robbins, Paul D., Khosla, Sundeep |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449299/ https://www.ncbi.nlm.nih.gov/pubmed/37154858 http://dx.doi.org/10.18632/aging.204701 |
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