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Extracorporeal cardiopulmonary resuscitation for refractory OHCA: lessons from three randomized controlled trials—the trialists’ view
Extracorporeal cardiopulmonary resuscitation is a promising treatment for refractory out-of-hospital cardiac arrest. Three recent randomized trials (ARREST trial, Prague OHCA study, and INCEPTION trial) that addressed the clinical benefit of extracorporeal cardiopulmonary resuscitation in out-of-hos...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449372/ https://www.ncbi.nlm.nih.gov/pubmed/37480551 http://dx.doi.org/10.1093/ehjacc/zuad071 |
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author | Ubben, Johannes F H Heuts, Samuel Delnoij, Thijs S R Suverein, Martje M van de Koolwijk, Anina F van der Horst, Iwan C C Maessen, Jos G Bartos, Jason Kavalkova, Petra Rob, Daniel Yannopoulos, Demetris Bělohlávek, Jan Lorusso, Roberto van de Poll, Marcel C G |
author_facet | Ubben, Johannes F H Heuts, Samuel Delnoij, Thijs S R Suverein, Martje M van de Koolwijk, Anina F van der Horst, Iwan C C Maessen, Jos G Bartos, Jason Kavalkova, Petra Rob, Daniel Yannopoulos, Demetris Bělohlávek, Jan Lorusso, Roberto van de Poll, Marcel C G |
author_sort | Ubben, Johannes F H |
collection | PubMed |
description | Extracorporeal cardiopulmonary resuscitation is a promising treatment for refractory out-of-hospital cardiac arrest. Three recent randomized trials (ARREST trial, Prague OHCA study, and INCEPTION trial) that addressed the clinical benefit of extracorporeal cardiopulmonary resuscitation in out-of-hospital cardiac arrest yielded seemingly diverging results. The evidence for extracorporeal cardiopulmonary resuscitation in out-of-hospital cardiac arrest, derived from three recent randomized controlled trials, is not contradictory but rather complementary. Excellent results can be achieved with a very high level of dedication, provided that strict selection criteria are applied. However, pragmatic implementation of extracorporeal cardiopulmonary resuscitation does not necessarily lead to improved outcome of refractory out-of-hospital cardiac arrest. Centres that are performing extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest or aspire to do so should critically evaluate whether they are able to meet the pre-requisites that are needed to conduct an effective extracorporeal cardiopulmonary resuscitation programme. |
format | Online Article Text |
id | pubmed-10449372 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-104493722023-08-25 Extracorporeal cardiopulmonary resuscitation for refractory OHCA: lessons from three randomized controlled trials—the trialists’ view Ubben, Johannes F H Heuts, Samuel Delnoij, Thijs S R Suverein, Martje M van de Koolwijk, Anina F van der Horst, Iwan C C Maessen, Jos G Bartos, Jason Kavalkova, Petra Rob, Daniel Yannopoulos, Demetris Bělohlávek, Jan Lorusso, Roberto van de Poll, Marcel C G Eur Heart J Acute Cardiovasc Care Review Extracorporeal cardiopulmonary resuscitation is a promising treatment for refractory out-of-hospital cardiac arrest. Three recent randomized trials (ARREST trial, Prague OHCA study, and INCEPTION trial) that addressed the clinical benefit of extracorporeal cardiopulmonary resuscitation in out-of-hospital cardiac arrest yielded seemingly diverging results. The evidence for extracorporeal cardiopulmonary resuscitation in out-of-hospital cardiac arrest, derived from three recent randomized controlled trials, is not contradictory but rather complementary. Excellent results can be achieved with a very high level of dedication, provided that strict selection criteria are applied. However, pragmatic implementation of extracorporeal cardiopulmonary resuscitation does not necessarily lead to improved outcome of refractory out-of-hospital cardiac arrest. Centres that are performing extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest or aspire to do so should critically evaluate whether they are able to meet the pre-requisites that are needed to conduct an effective extracorporeal cardiopulmonary resuscitation programme. Oxford University Press 2023-07-22 /pmc/articles/PMC10449372/ /pubmed/37480551 http://dx.doi.org/10.1093/ehjacc/zuad071 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Review Ubben, Johannes F H Heuts, Samuel Delnoij, Thijs S R Suverein, Martje M van de Koolwijk, Anina F van der Horst, Iwan C C Maessen, Jos G Bartos, Jason Kavalkova, Petra Rob, Daniel Yannopoulos, Demetris Bělohlávek, Jan Lorusso, Roberto van de Poll, Marcel C G Extracorporeal cardiopulmonary resuscitation for refractory OHCA: lessons from three randomized controlled trials—the trialists’ view |
title | Extracorporeal cardiopulmonary resuscitation for refractory OHCA: lessons from three randomized controlled trials—the trialists’ view |
title_full | Extracorporeal cardiopulmonary resuscitation for refractory OHCA: lessons from three randomized controlled trials—the trialists’ view |
title_fullStr | Extracorporeal cardiopulmonary resuscitation for refractory OHCA: lessons from three randomized controlled trials—the trialists’ view |
title_full_unstemmed | Extracorporeal cardiopulmonary resuscitation for refractory OHCA: lessons from three randomized controlled trials—the trialists’ view |
title_short | Extracorporeal cardiopulmonary resuscitation for refractory OHCA: lessons from three randomized controlled trials—the trialists’ view |
title_sort | extracorporeal cardiopulmonary resuscitation for refractory ohca: lessons from three randomized controlled trials—the trialists’ view |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449372/ https://www.ncbi.nlm.nih.gov/pubmed/37480551 http://dx.doi.org/10.1093/ehjacc/zuad071 |
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