Tenofovir vaginal film as a potential MPT product against HIV-1 and HSV-2 acquisition: formulation development and preclinical assessment in non-human primates

Tenofovir (TFV) is an adenosine nucleotide analog with activity against HIV and HSV-2. Secondary analyses of clinical trials evaluating TFV gel as pre-exposure prophylaxis (PrEP) for HIV have shown that gel formulations of TFV provide significant protection against both HIV and HSV-2 acquisition in...

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Detalles Bibliográficos
Autores principales: Patel, Sravan Kumar, Agashe, Hrushikesh, Patton, Dorothy L., Sweeney, Yvonne, Beamer, May A., Hendrix, Craig W., Hillier, Sharon L., Rohan, Lisa C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Reproductive Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449455/
https://www.ncbi.nlm.nih.gov/pubmed/37638127
http://dx.doi.org/10.3389/frph.2023.1217835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449455/
https://www.ncbi.nlm.nih.gov/pubmed/37638127
http://dx.doi.org/10.3389/frph.2023.1217835

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