Development of a methodology for large-scale production of prions for biological and structural studies

Prion diseases are a group of infectious neurodegenerative diseases produced by the conversion of the normal prion protein (PrP(C)) into the disease-associated form (PrP(Sc)). Extensive evidence indicate that the main or sole component of the infectious agent is PrP(Sc), which can replicate in affec...

Descripción completa

Detalles Bibliográficos
Autores principales: Concha-Marambio, Luis, Wang, Fei, Armijo, Enrique, Gorski, Damian, Ramirez, Frank, Scowcroft, Andrew, Pritzkow, Sandra, Soto, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449461/
https://www.ncbi.nlm.nih.gov/pubmed/37635939
http://dx.doi.org/10.3389/fmolb.2023.1184029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449461/
https://www.ncbi.nlm.nih.gov/pubmed/37635939
http://dx.doi.org/10.3389/fmolb.2023.1184029

Ejemplares similares