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Development of a methodology for large-scale production of prions for biological and structural studies
Prion diseases are a group of infectious neurodegenerative diseases produced by the conversion of the normal prion protein (PrP(C)) into the disease-associated form (PrP(Sc)). Extensive evidence indicate that the main or sole component of the infectious agent is PrP(Sc), which can replicate in affec...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449461/ https://www.ncbi.nlm.nih.gov/pubmed/37635939 http://dx.doi.org/10.3389/fmolb.2023.1184029 |