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Redefining pleiotropic drug resistance in a pathogenic yeast: Pdr1 functions as a sensor of cellular stresses in Candida glabrata

Candida glabrata is a prominent opportunistic fungal pathogen of humans. The increasing incidence of C. glabrata infections is attributed to both innate and acquired resistance to antifungals. Previous studies suggest the transcription factor Pdr1 and several target genes encoding ABC transporters a...

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Detalles Bibliográficos
Autores principales: Gale, Andrew N., Pavesic, Matthew W., Nickels, Timothy J., Xu, Zhuwei, Cormack, Brendan P., Cunningham, Kyle W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449514/
https://www.ncbi.nlm.nih.gov/pubmed/37358297
http://dx.doi.org/10.1128/msphere.00254-23