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Redefining pleiotropic drug resistance in a pathogenic yeast: Pdr1 functions as a sensor of cellular stresses in Candida glabrata
Candida glabrata is a prominent opportunistic fungal pathogen of humans. The increasing incidence of C. glabrata infections is attributed to both innate and acquired resistance to antifungals. Previous studies suggest the transcription factor Pdr1 and several target genes encoding ABC transporters a...
Autores principales: | Gale, Andrew N., Pavesic, Matthew W., Nickels, Timothy J., Xu, Zhuwei, Cormack, Brendan P., Cunningham, Kyle W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449514/ https://www.ncbi.nlm.nih.gov/pubmed/37358297 http://dx.doi.org/10.1128/msphere.00254-23 |
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