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Therapeutic potential of Bacillus phage lysin PlyB in ocular infections

Bacteriophage lytic enzymes (i.e., phage lysins) are a trending alternative for general antibiotics to combat growing antimicrobial resistance. Gram-positive Bacillus cereus causes one of the most severe forms of intraocular infection, often resulting in complete vision loss. It is an inherently β-l...

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Detalles Bibliográficos
Autores principales: Mursalin, Md Huzzatul, Astley, Roger, Coburn, Phillip S., Bagaruka, Eddy, Hunt, Jonathan J., Fischetti, Vincent A., Callegan, Michelle C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449515/
https://www.ncbi.nlm.nih.gov/pubmed/37273201
http://dx.doi.org/10.1128/msphere.00044-23