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Single-spore germination analyses reveal that calcium released during Clostridioides difficile germination functions in a feedforward loop

Clostridioides difficile infections begin when its metabolically dormant spores germinate in response to sensing bile acid germinants alongside amino acid and divalent cation co-germinants in the small intestine. While bile acid germinants are essential for C. difficile spore germination, it is curr...

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Detalles Bibliográficos
Autores principales: Ribis, John W., Melo, Luana, Shrestha, Shailab, Giacalone, David, Rodriguez, Enrique E., Shen, Aimee, Rohlfing, Amy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449524/
https://www.ncbi.nlm.nih.gov/pubmed/37338207
http://dx.doi.org/10.1128/msphere.00005-23