Clinical-mediated discovery of pyroptosis in CD8(+) T cell and NK cell reveals melanoma heterogeneity by single-cell and bulk sequence

Histologically, melanoma tissues had fewer positive cells percentage of pyroptosis-related genes (PRGs), GZMA, GSDMB, NLRP1, IL18, and CHMP4A in epidermal than in normal skin. Pyroptosis, a new frontier in cancer, affects the tumor microenvironment and tumor immunotherapy. Nevertheless, the role of...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Bai, Yun, Ma, Xiao-Xuan, Song, Jian-Kun, Luo, Yue, Fei, Xiao-Ya, Ru, Yi, Luo, Ying, Jiang, Jing-Si, Zhang, Zhan, Yang, Dan, Xue, Ting-Ting, Zhang, Hui-Ping, Liu, Tai-Yi, Xiang, Yan-Wei, Kuai, Le, Liu, Ye-Qiang, Li, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449777/
https://www.ncbi.nlm.nih.gov/pubmed/37620327
http://dx.doi.org/10.1038/s41419-023-06068-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449777/
https://www.ncbi.nlm.nih.gov/pubmed/37620327
http://dx.doi.org/10.1038/s41419-023-06068-5

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