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A qPCR technology for direct quantification of methylation in untreated DNA

DNA methylation is important for gene expression and alterations in DNA methylation are involved in the development and progression of cancer and other major diseases. Analysis of DNA methylation patterns has until now been dependent on either a chemical or an enzymatic pre-treatment, which are both...

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Detalles Bibliográficos
Autores principales: Bendixen, Kamilla Kolding, Mindegaard, Maria, Epistolio, Samantha, Dazio, Giulia, Marchi, Francesco, Spina, Paolo, Arnspang, Eva C., Soerensen, Mette, Christensen, Ulf Bech, Frattini, Milo, Petersen, Rasmus Koefoed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449789/
https://www.ncbi.nlm.nih.gov/pubmed/37620381
http://dx.doi.org/10.1038/s41467-023-40873-y