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Development of a three-dimensional organoid model to explore early retinal phenotypes associated with Alzheimer’s disease
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by the accumulation of Aβ plaques and neurofibrillary tangles, resulting in synaptic loss and neurodegeneration. The retina is an extension of the central nervous system within the eye, sharing many structural similar...
Autores principales: | Lavekar, Sailee S., Harkin, Jade, Hernandez, Melody, Gomes, Cátia, Patil, Shruti, Huang, Kang-Chieh, Puntambekar, Shweta S., Lamb, Bruce T., Meyer, Jason S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449801/ https://www.ncbi.nlm.nih.gov/pubmed/37620502 http://dx.doi.org/10.1038/s41598-023-40382-4 |
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