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Expression of Cyclin E1 in hepatic stellate cells is critical for the induction and progression of liver fibrosis and hepatocellular carcinoma in mice

Hepatocellular carcinoma (HCC) is one of the most severe malignancies with increasing incidence and limited treatment options. Typically, HCC develops during a multistep process involving chronic liver inflammation and liver fibrosis. The latter is characterized by the accumulation of extracellular...

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Detalles Bibliográficos
Autores principales: Otto, Julia, Verwaayen, Anna, Penners, Christian, Hundertmark, Jana, Lin, Cheng, Kallen, Carina, Paffen, Daniela, Otto, Tobias, Berger, Hilmar, Tacke, Frank, Weiskirchen, Ralf, Nevzorova, Yulia A., Bartneck, Matthias, Trautwein, Christian, Sonntag, Roland, Liedtke, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449804/
https://www.ncbi.nlm.nih.gov/pubmed/37620309
http://dx.doi.org/10.1038/s41419-023-06077-4