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Expression of Cyclin E1 in hepatic stellate cells is critical for the induction and progression of liver fibrosis and hepatocellular carcinoma in mice
Hepatocellular carcinoma (HCC) is one of the most severe malignancies with increasing incidence and limited treatment options. Typically, HCC develops during a multistep process involving chronic liver inflammation and liver fibrosis. The latter is characterized by the accumulation of extracellular...
Autores principales: | Otto, Julia, Verwaayen, Anna, Penners, Christian, Hundertmark, Jana, Lin, Cheng, Kallen, Carina, Paffen, Daniela, Otto, Tobias, Berger, Hilmar, Tacke, Frank, Weiskirchen, Ralf, Nevzorova, Yulia A., Bartneck, Matthias, Trautwein, Christian, Sonntag, Roland, Liedtke, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449804/ https://www.ncbi.nlm.nih.gov/pubmed/37620309 http://dx.doi.org/10.1038/s41419-023-06077-4 |
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