Split‐Cas9‐based targeted gene editing and nanobody‐mediated proteolysis‐targeting chimeras optogenetically coordinated regulation of Survivin to control the fate of cancer cells

BACKGROUND: Precise regulation of partial critical proteins in cancer cells, such as anti‐apoptotic proteins, is one of the crucial strategies for treating cancer and discovering related molecular mechanisms. Still, it is also challenging in actual research and practice. The widely used CRISPR/Cas9‐...

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Detalles Bibliográficos
Autores principales: Deng, Changping, Li, Shihui, Liu, Yuping, Bao, Wen, Xu, Chengnan, Zheng, Wenyun, Wang, Meiyan, Ma, Xingyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449816/
https://www.ncbi.nlm.nih.gov/pubmed/37620295
http://dx.doi.org/10.1002/ctm2.1382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449816/
https://www.ncbi.nlm.nih.gov/pubmed/37620295
http://dx.doi.org/10.1002/ctm2.1382

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