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Fanconi anemia associated protein 20 (FAAP20) plays an essential role in homology-directed repair of DNA double-strand breaks

FAAP20 is a Fanconi anemia (FA) protein that associates with the FA core complex to promote FANCD2/FANCI monoubiquitination and activate the damage response to interstrand crosslink damage. Here, we report that FAAP20 has a marked role in homologous recombination at a DNA double-strand break not ass...

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Detalles Bibliográficos
Autores principales: Palovcak, Anna, Yuan, Fenghua, Verdun, Ramiro, Luo, Liang, Zhang, Yanbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449828/
https://www.ncbi.nlm.nih.gov/pubmed/37620397
http://dx.doi.org/10.1038/s42003-023-05252-9