Cargando…
Fanconi anemia associated protein 20 (FAAP20) plays an essential role in homology-directed repair of DNA double-strand breaks
FAAP20 is a Fanconi anemia (FA) protein that associates with the FA core complex to promote FANCD2/FANCI monoubiquitination and activate the damage response to interstrand crosslink damage. Here, we report that FAAP20 has a marked role in homologous recombination at a DNA double-strand break not ass...
Autores principales: | Palovcak, Anna, Yuan, Fenghua, Verdun, Ramiro, Luo, Liang, Zhang, Yanbin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449828/ https://www.ncbi.nlm.nih.gov/pubmed/37620397 http://dx.doi.org/10.1038/s42003-023-05252-9 |
Ejemplares similares
-
Prolyl isomerization of FAAP20 catalyzed by PIN1 regulates the Fanconi anemia pathway
por: Wang, Jingming, et al.
Publicado: (2019) -
Maintenance of genome stability by Fanconi anemia proteins
por: Palovcak, Anna, et al.
Publicado: (2017) -
Architecture and DNA Recognition Elements of the Fanconi Anemia FANCM-FAAP24 Complex
por: Coulthard, Rachel, et al.
Publicado: (2013) -
Fanconi anemia pathway as a prospective target for cancer intervention
por: Liu, Wenjun, et al.
Publicado: (2020) -
The Fanconi anemia associated protein FAAP24 uses two substrate specific binding surfaces for DNA recognition
por: Wienk, Hans, et al.
Publicado: (2013)