Immunotherapy targeting different immune compartments in combination with radiation therapy induces regression of resistant tumors

Radiation therapy (RT) increases tumor response to CTLA-4 inhibition (CTLA4i) in mice and in some patients, yet deep responses are rare. To identify rational combinations of immunotherapy to improve responses we use models of triple negative breast cancer highly resistant to immunotherapy in female...

Descripción completa

Detalles Bibliográficos
Autores principales: Rudqvist, Nils-Petter, Charpentier, Maud, Lhuillier, Claire, Wennerberg, Erik, Spada, Sheila, Sheridan, Caroline, Zhou, Xi Kathy, Zhang, Tuo, Formenti, Silvia C., Sims, Jennifer S., Alonso, Alicia, Demaria, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449830/
https://www.ncbi.nlm.nih.gov/pubmed/37620372
http://dx.doi.org/10.1038/s41467-023-40844-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449830/
https://www.ncbi.nlm.nih.gov/pubmed/37620372
http://dx.doi.org/10.1038/s41467-023-40844-3

Ejemplares similares