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Immunotherapy targeting different immune compartments in combination with radiation therapy induces regression of resistant tumors
Radiation therapy (RT) increases tumor response to CTLA-4 inhibition (CTLA4i) in mice and in some patients, yet deep responses are rare. To identify rational combinations of immunotherapy to improve responses we use models of triple negative breast cancer highly resistant to immunotherapy in female...
Autores principales: | Rudqvist, Nils-Petter, Charpentier, Maud, Lhuillier, Claire, Wennerberg, Erik, Spada, Sheila, Sheridan, Caroline, Zhou, Xi Kathy, Zhang, Tuo, Formenti, Silvia C., Sims, Jennifer S., Alonso, Alicia, Demaria, Sandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449830/ https://www.ncbi.nlm.nih.gov/pubmed/37620372 http://dx.doi.org/10.1038/s41467-023-40844-3 |
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