Acquired resistance to anti-PD1 therapy in patients with NSCLC associates with immunosuppressive T cell phenotype

Immune checkpoint inhibitor treatment has the potential to prolong survival in non-small cell lung cancer (NSCLC), however, some of the patients develop resistance following initial response. Here, we analyze the immune phenotype of matching tumor samples from a cohort of NSCLC patients showing good...

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Detalles Bibliográficos
Autores principales: Hiltbrunner, Stefanie, Cords, Lena, Kasser, Sabrina, Freiberger, Sandra N., Kreutzer, Susanne, Toussaint, Nora C., Grob, Linda, Opitz, Isabelle, Messerli, Michael, Zoche, Martin, Soltermann, Alex, Rechsteiner, Markus, van den Broek, Maries, Bodenmiller, Bernd, Curioni-Fontecedro, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449840/
https://www.ncbi.nlm.nih.gov/pubmed/37620318
http://dx.doi.org/10.1038/s41467-023-40745-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449840/
https://www.ncbi.nlm.nih.gov/pubmed/37620318
http://dx.doi.org/10.1038/s41467-023-40745-5

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