Structural basis of lipid-droplet localization of 17-beta-hydroxysteroid dehydrogenase 13

Hydroxysteroid 17-beta-dehydrogenase 13 (HSD17B13) is a hepatic lipid droplet-associated enzyme that is upregulated in patients with non-alcoholic fatty liver disease. Recently, there have been several reports that predicted loss of function variants in HSD17B13 protect against the progression of st...

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Detalles Bibliográficos
Autores principales: Liu, Shenping, Sommese, Ruth F., Nedoma, Nicole L., Stevens, Lucy Mae, Dutra, Jason K., Zhang, Liying, Edmonds, David J., Wang, Yang, Garnsey, Michelle, Clasquin, Michelle F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449848/
https://www.ncbi.nlm.nih.gov/pubmed/37620305
http://dx.doi.org/10.1038/s41467-023-40766-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449848/
https://www.ncbi.nlm.nih.gov/pubmed/37620305
http://dx.doi.org/10.1038/s41467-023-40766-0

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