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Thermodynamic principle to enhance enzymatic activity using the substrate affinity

Understanding how to tune enzymatic activity is important not only for biotechnological applications, but also to elucidate the basic principles guiding the design and optimization of biological systems in nature. So far, the Michaelis-Menten equation has provided a fundamental framework of enzymati...

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Detalles Bibliográficos
Autores principales: Ooka, Hideshi, Chiba, Yoko, Nakamura, Ryuhei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449852/
https://www.ncbi.nlm.nih.gov/pubmed/37620340
http://dx.doi.org/10.1038/s41467-023-40471-y