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Targeting ANXA7/LAMP5-mTOR axis attenuates spinal cord injury by inhibiting neuronal apoptosis via enhancing autophagy in mice

Spinal cord injury (SCI) could lead to severe disabilities in motor and sensory functions, and cause a heavy burden on patient physiology and psychology due to lack of specific repair measures so far. ANXA7 is an annexin with Ca(2+) -dependent GTPase activity, which were mainly expressed in neuron i...

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Detalles Bibliográficos
Autores principales: Li, Na, Chen, Lu, Zhao, Xiaoqing, Gu, Chi, Chang, Yong, Feng, Shiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449888/
https://www.ncbi.nlm.nih.gov/pubmed/37620352
http://dx.doi.org/10.1038/s41420-023-01612-w