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Targeting ANXA7/LAMP5-mTOR axis attenuates spinal cord injury by inhibiting neuronal apoptosis via enhancing autophagy in mice
Spinal cord injury (SCI) could lead to severe disabilities in motor and sensory functions, and cause a heavy burden on patient physiology and psychology due to lack of specific repair measures so far. ANXA7 is an annexin with Ca(2+) -dependent GTPase activity, which were mainly expressed in neuron i...
Autores principales: | Li, Na, Chen, Lu, Zhao, Xiaoqing, Gu, Chi, Chang, Yong, Feng, Shiqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449888/ https://www.ncbi.nlm.nih.gov/pubmed/37620352 http://dx.doi.org/10.1038/s41420-023-01612-w |
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