Cargando…

Autophagy deficiency protects against ocular hypertension and neurodegeneration in experimental and spontaneous glaucoma mouse models

Glaucoma is a group of diseases that leads to chronic degeneration of retinal ganglion cell (RGC) axons and progressive loss of RGCs, resulting in vision loss. While aging and elevated intraocular pressure (IOP) have been identified as the main contributing factors to glaucoma, the molecular mechani...

Descripción completa

Detalles Bibliográficos
Autores principales: Dixon, Angela, Shim, Myoung Sup, Nettesheim, April, Coyne, Aislyn, Su, Chien-Chia, Gong, Haiyan, Liton, Paloma B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449899/
https://www.ncbi.nlm.nih.gov/pubmed/37620383
http://dx.doi.org/10.1038/s41419-023-06086-3