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Vemurafenib inhibits necroptosis in normal and pathological conditions as a RIPK1 antagonist
Necroptosis, a programmed cell death with necrotic-like morphology, has been recognized as an important driver in various inflammatory diseases. Inhibition of necroptosis has shown potential promise in the therapy of multiple human diseases. However, very few necroptosis inhibitors are available for...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449909/ https://www.ncbi.nlm.nih.gov/pubmed/37620300 http://dx.doi.org/10.1038/s41419-023-06065-8 |