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Saponin-based adjuvants enhance antigen cross-presentation in human CD11c(+) CD1c(+) CD5(−) CD163(+) conventional type 2 dendritic cells

BACKGROUND: Adjuvants are key for effective vaccination against cancer and chronic infectious diseases. Saponin-based adjuvants (SBAs) are unique among adjuvants in their ability to induce robust cell-mediated immune responses in addition to antibody responses. Recent preclinical studies revealed th...

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Detalles Bibliográficos
Autores principales: Ho, Nataschja I, Huis in 't Veld, Lisa G M, van Eck van der Sluijs, Jesper, Heuts, Branco M H, Looman, Maaike W G, Kers-Rebel, Esther D, van den Dries, Koen, Dolstra, Harry, Martens, Joost H A, Hobo, Willemijn, Adema, Gosse J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450066/
https://www.ncbi.nlm.nih.gov/pubmed/37612044
http://dx.doi.org/10.1136/jitc-2023-007082