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Double-negative-2 B cells are the major synovial plasma cell precursor in rheumatoid arthritis

B cells are key pathogenic drivers of chronic inflammation in rheumatoid arthritis (RA). There is limited understanding of the relationship between synovial B cell subsets and pathogenic antibody secreting cells (ASCs). This knowledge is crucial for the development of more targeted B-cell depleting...

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Detalles Bibliográficos
Autores principales: Wing, Elinor, Sutherland, Catherine, Miles, Katherine, Gray, David, Goodyear, Carl S., Otto, Thomas D., Breusch, Stefan, Cowan, Graeme, Gray, Mohini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450142/
https://www.ncbi.nlm.nih.gov/pubmed/37638026
http://dx.doi.org/10.3389/fimmu.2023.1241474