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Evolution of molecular switches for regulation of transgene expression by clinically licensed gluconate

Synthetic biology holds great promise to improve the safety and efficacy of future gene and engineered cell therapies by providing new means of endogenous or exogenous control of the embedded therapeutic programs. Here, we focused on gluconate as a clinically licensed small-molecule inducer and engi...

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书目详细资料
Autores principales: Teixeira, Ana Palma, Xue, Shuai, Huang, Jinbo, Fussenegger, Martin
格式: Online 文件 Texto
语言:English
出版: Oxford University Press 2023
主题:
在线阅读:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450161/
https://www.ncbi.nlm.nih.gov/pubmed/37497781
http://dx.doi.org/10.1093/nar/gkad600