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Evolution of molecular switches for regulation of transgene expression by clinically licensed gluconate

Synthetic biology holds great promise to improve the safety and efficacy of future gene and engineered cell therapies by providing new means of endogenous or exogenous control of the embedded therapeutic programs. Here, we focused on gluconate as a clinically licensed small-molecule inducer and engi...

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Detalhes bibliográficos
Principais autores: Teixeira, Ana Palma, Xue, Shuai, Huang, Jinbo, Fussenegger, Martin
Formato: Online Atigo Texto
Idioma:English
Publicado em: Oxford University Press 2023
Assuntos:
Acesso em linha:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450161/
https://www.ncbi.nlm.nih.gov/pubmed/37497781
http://dx.doi.org/10.1093/nar/gkad600