A clickable melphalan for monitoring DNA interstrand crosslink accumulation and detecting ICL repair defects in Fanconi anemia patient cells

Fanconi anemia (FA) is a genetic disorder associated with developmental defects, bone marrow failure and cancer. The FA pathway is crucial for the repair of DNA interstrand crosslinks (ICLs). In this study, we have developed and characterized a new tool to investigate ICL repair: a clickable version...

Descripción completa

Detalles Bibliográficos
Autores principales: Berrada, Sara, Martínez-Balsalobre, Elena, Larcher, Lise, Azzoni, Violette, Vasquez, Nadia, Da Costa, Mélanie, Abel, Sébastien, Audoly, Gilles, Lee, Lara, Montersino, Camille, Castellano, Rémy, Combes, Sébastien, Gelot, Camille, Ceccaldi, Raphaël, Guervilly, Jean-Hugues, Soulier, Jean, Lachaud, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450163/
https://www.ncbi.nlm.nih.gov/pubmed/37395445
http://dx.doi.org/10.1093/nar/gkad559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450163/
https://www.ncbi.nlm.nih.gov/pubmed/37395445
http://dx.doi.org/10.1093/nar/gkad559

Ejemplares similares