Structural basis for specific DNA sequence motif recognition by the TFAP2 transcription factors

The TFAP2 family regulates gene expression during differentiation, development, and organogenesis, and includes five homologs in humans. They all possess a highly conserved DNA binding domain (DBD) followed by a helix-span-helix (HSH) domain. The DBD-HSH tandem domain specifically binds to a GCC(N3)...

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Detalles Bibliográficos
Autores principales: Liu, Ke, Xiao, Yuqing, Gan, Linyao, Li, Weifang, Zhang, Jin, Min, Jinrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450164/
https://www.ncbi.nlm.nih.gov/pubmed/37409559
http://dx.doi.org/10.1093/nar/gkad583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450164/
https://www.ncbi.nlm.nih.gov/pubmed/37409559
http://dx.doi.org/10.1093/nar/gkad583

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