Predicting functional consequences of SNPs on mRNA translation via machine learning

The functional impact of single nucleotide polymorphisms (SNPs) on translation has yet to be considered when prioritizing disease-causing SNPs from genome-wide association studies (GWAS). Here we apply machine learning models to genome-wide ribosome profiling data to predict SNP function by forecast...

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Detalles Bibliográficos
Autores principales: Li, Zheyu, Chen, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450169/
https://www.ncbi.nlm.nih.gov/pubmed/37427781
http://dx.doi.org/10.1093/nar/gkad576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450169/
https://www.ncbi.nlm.nih.gov/pubmed/37427781
http://dx.doi.org/10.1093/nar/gkad576

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