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Predicting functional consequences of SNPs on mRNA translation via machine learning
The functional impact of single nucleotide polymorphisms (SNPs) on translation has yet to be considered when prioritizing disease-causing SNPs from genome-wide association studies (GWAS). Here we apply machine learning models to genome-wide ribosome profiling data to predict SNP function by forecast...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450169/ https://www.ncbi.nlm.nih.gov/pubmed/37427781 http://dx.doi.org/10.1093/nar/gkad576 |