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Retron-mediated multiplex genome editing and continuous evolution in Escherichia coli

While there are several genome editing techniques available, few are suitable for dynamic and simultaneous mutagenesis of arbitrary targeted sequences in prokaryotes. Here, to address these limitations, we present a versatile and multiplex retron-mediated genome editing system (REGES). First, throug...

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Detalles Bibliográficos
Autores principales: Liu, Wenqian, Zuo, Siqi, Shao, Youran, Bi, Ke, Zhao, Jiarun, Huang, Lei, Xu, Zhinan, Lian, Jiazhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450171/
https://www.ncbi.nlm.nih.gov/pubmed/37471041
http://dx.doi.org/10.1093/nar/gkad607